In 2017, gabapentin was the eleventh most prescribed medication. It was designed by the scientists at Parke-Davis to be an analogue (compound that has a similar structure to another) of the neurotransmitter gamma-aminobutyric acid or GABA.
The principle role of this neurotransmitter is to create a calming effect. Gabapentin tablets have a variety of Food and Drug Administration (FDA) approved uses and this includes using gabapentin for nerve pain and epilepsy. Another reason, apart from the accessibility, to buy gabapentin online, is for the treatment of anxiety disorders. This is an increasingly preferred off-label application.
GABA is key in how the treatment works. Scientists had established that those experiencing epileptic attacks were deficient in the GABA neurotransmitter. However, this substance was unable to cross the blood-brain barrier and enter the CNS where it was needed. This limitation posed a barrier for seizure treatment.
Fortunately, the issue of crossing the blood-brain barrier was solved by the researchers at Parke-Davis when they incorporated GABA into a lipophilic (a substance which is easily dissolved in lipids) cyclohexane ring. The result was a GABA analogue, in the form of this medication, which can enter the brain more easily through the blood circulatory system.
Gabapentin has a similar structure to the chief neurotransmitter of the CNS (GABA), but it functions in a very different manner. Researchers are in fact still exploring this medication's mechanism of action, but the former has been established.
This white crystalline powder was first approved for the use of epileptic seizures, but the anti-convulsant properties of gabapentin 300 mg would only be proven useful when combined with other anti-epileptic medicines.
By the mid-90's the anti-epileptic uses of this medication were not the only benefits. Those with neuropathic pain were using gabapentin for pain relief, especially in cases where traditional pain relievers and even opioid medications were ineffective.
You can also buy gabapentin for the treatment of:
The Federation of Neurological Sciences acknowledges the use of gabapentin for pain, particularly for the treatment of central pain syndrome. You can buy gabapentin online, including brands like Neurontin and Gralise. We sell approved generic and brand options on this website.
This list includes several advantages, such as the following:
The amount of therapeutic administered depends on several factors:
Age: Gabapentin tablets are generally only recommended for use by adults.
Bodyweight: Obesity is also known to affect all aspects of pharamcokinetics (pharmacology associated with the movement of medications through the body).
Gender: In 2013, the FDA revealed the existence of scientific data proving that women are at a higher risk of sedation when using certain hypnotics. It was further revealed that females tend to exhibit impaired driving proficiency after a nightly administration of these medications. It is for this reason that women are normally prescribed lower dosages of therapeutics.
Condition: The gabapentin dosage is dependent on the condition you are using the medication for. For example, the gabapentin dosage for chronic pain will differ from the dose of gabapentin for anxiety.
The general dosing guide is as follows:
300-600 mg, three times a day for adults
300 mg up to three times a day. Use as needed depending on level of pain.
Restless legs syndrome:
600 mg, once a day
300 mg, once a day
Common, mild gabapentin side effects may include:
Infrequent side effects:
The FDA required a new warning be added to the labelling of gabapentinoids (GABA analogues), concerning the increased risk of respiratory difficulties. When you buy gabapentin it should be noted that using this medication in conjunction with other CNS depressants puts you at risk for serious breathing problems. Elderly patients, using gabapentin for pain and other ailments, should exercise special caution in these circumstances.
Following respective usage guidelines and precautions will ensure benefits are achieved, with minimal unwanted effects. Gabapentin has a high efficacy rate and has proven to be a safe and effective medication.
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